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Although this region of the enzyme has been confirmed to bind GSH and the C28-C31 pair has been observed to be necessary for the reduction of GSSG, there is no explicit evidence of how electrons are transmitted to the GR domain

doi: 10.5152/tjg.2020.19568

however, its function may be disrupted in individuals with diabetes, resulting in IR and impairing glucose uptake [79]

Infusion After the baseline POPE 13 C-MRS scan (see below), animals were administered a (20% w/v) solution of (99%) uniformly 13 C-labelled glucose ([U- 13 C 6 ]-Glc) solution (CK Isotopes Ltd.) via a sub-cutaneous (s.c.) cannula connected with an infusion pump (PHD 2000, Harvard Apparatus) which was inserted in the animals flank

High resolution FDG-microPET of carotid atherosclerosis: plaque components underlying enhanced FDG uptake